A statistical analysis of 626 biopsy done between march-1971 and february-1981 at the depa￢rtment of Otolaryngology, Chosun University Hospital was carried out. The results are as follows;
1. Among 14, 569 new patients at E.N.T. department, 626 patients (4.3%) took diagnostic
biopsy. Male patients were 392 (63%), female 234 (37%).
Among 626 patients who had taken diagnostic biopsy, 34 patients (5.4%) had to take
repeated biopsies, especially. in case of nasal and paranasal cavity and larynx.
2. The site of biopsy included neck (24.3%), larynx (15.5%), nose and paranasal sinuses
(14.2%), tongue (12.0%), other parts of oral cavity (8.0%) and oropharynx (6.2%). 3. Histologic findings are as below;
primary malignancy 34.71% specific inflammation 11.00/0 nonspecific inflammation 23.5% secondary malignancy 5.3% benign tumor 15.3% cyst 3.5%
4. Of 217 patients with primary malignancy, male to female ratio is 3.3 : 1, and most prominent in patients between 40 s and 60 s (81.8%).
Cytologic finding included squamous cell carcinoma (60.4%), malignant lymphoma (12. 4%) and undifferentiated carcinoma (4.1%).
5. Of 147 patients with nonspecific inflammation, there is no particular difference in age and sex. ratio.
6. 96 patients with benign tumor are almost distributed between 20 s and 40 s (57. 3%). And almost all the tumors are originated either from epithelial cell (66.7%) or mesenchymal cell (27.0%).
7. 69 patients with specific inflammation were found-to have the nature of tuberculosis (89. 9%).
8. There are 33 patients with metastatic tumors and all the metastatic tumors are found on cervical lymph node except one (97,%). Their primary focuses included G-I tract (25/0),
hepatobiliary tract (12.5%), bronchial tree (9.4%), breast (6.31) and unknown (37.5%). 9. Cysts were found in 22 patients with same incidence in both sexes and most frequently
noticed in the site of neck (45.5%).
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